- Home
- Middle East
- UAE
- NYU Abu Dhabi researchers develop materials for oral delivery of insulin medication
NYU Abu Dhabi Researchers Develop Materials For Oral Delivery Of Insulin Medication
Umer Jamshaid Published April 07, 2021 | 01:00 PM
ABU DHABI, (UrduPoint / Pakistan Point News / WAM - 07th Apr, 2021) A revolutionary technology developed within the Trabolsi Research Group at NYU Abu Dhabi (NYUAD) could dramatically improve the well-being of diabetic patients through a simple and straightforward way: an insulin oral delivery system that could replace traditional subcutaneous injections without the side effects caused by frequent injection.
Using prepared layers of nanosheets with insulin loaded in between layers to protect it, researchers developed gastro-resistant imine-linked-covalent organic framework nanoparticles (nCOFs) that exhibited insulin protection in the stomach as well in diabetic test subjects whose sugar levels completely returned to normal within two hours after swallowing the nanoparticles. Led by NYUAD’s Research Scientist Farah Benyettou and Programme Head of Chemistry Ali Trabolsi, the findings were published today in Chemical Science.
Compared to the two US food and Drug Administration (FDA) approved technologies for the oral delivery of insulin, the system developed at NYUAD is biocompatible, highly stable in the stomach, specific, and able to deliver the right amount of insulin based on the diabetic subject’s blood sugar levels.
This treatment represents a step forward in treating this disease that is the seventh leading cause of death worldwide.
"Our work overcomes insulin oral delivery barriers by using insulin-loaded nCOF nanoparticles which exhibit insulin protection in the stomach as well as a glucose-responsive release," said Benyettou.
"This technology responds quickly to an elevation in blood sugar, but would promptly shut off to prevent insulin overdose and will dramatically improve the well-being of diabetic patients across the UAE and worldwide," she added.
The development of this treatment was in collaboration with an international team of researchers from Algeria, Spain, Saudi Arabia, and the United Kingdom. The project was completed with the help of NYUAD’s Core Platform Technology. A US patent application is pending for this innovative technology.
Related Topics
Recent Stories
Currency Rate In Pakistan - Dollar, Euro, Pound, Riyal Rates On 27 April 2024
Today Gold Rate in Pakistan 27 April 2024
HEC reviews curricula for environmental sciences degree programme
ICC Asia looking forward to an action-packed Asia Cricket Week
Yuvraj Singh named ICC Men’s T20 World Cup 2024 Ambassador
Greece hands Olympic flame to 2024 Paris Games hosts
Two Kyiv hospitals evacuating over feared Russian strikes
World must act on neurotech revolution, say experts
Charles & Catherine's cancer diagnoses
Champions Alcaraz and Sabalenka through in Madrid Open
King Charles to resume some public duties during cancer treatment: palace
US defense chief announces $6 bn in security aid for Ukraine
More Stories From Middle East
-
UAE announces ‘Zero Bureaucracy Program’ to reduce bureaucracy
3 months ago -
COP28 President-Designate welcomes Transitional Committee agreement to operationalise Loss and Damag ..
6 months ago -
Global Media Congress 2023 to feature Co-Production Majlis as a new networking platform
6 months ago -
Young female athletes shine at Abu Dhabi World Youth Jiu-Jitsu Championship
6 months ago -
King of Jordan receives Abdullah bin Zayed and ministers participating in Arab coordination meeting
6 months ago -
Abdullah bin Zayed participates in coordination meeting of Arab foreign ministers, joint meeting wit ..
6 months ago
-
3rd annual conference of Emirates Society of Clinical Microbiology kicks off in Dubai
6 months ago -
SIBF 2023 hosts Nobel laureate to discuss emergence of ‘Afrofuturism’ in global discourse
6 months ago -
ALC announces winners of Kanz Al Jeel Award 2023
6 months ago -
SIBF turns spotlight on remarkable contributions of women
6 months ago -
Global assets in spot bitcoin ETFs hit $4.16 billion
6 months ago -
Rescuers struggle to find Nepal quake survivors as deaths reach 157
6 months ago